1XKB
FACTOR XA COMPLEXED WITH A SYNTHETIC INHIBITOR FX-2212A,(2S)-(3'-AMIDINO-3-BIPHENYLYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID
Summary for 1XKB
Entry DOI | 10.2210/pdb1xkb/pdb |
Descriptor | BLOOD COAGULATION FACTOR XA, CALCIUM ION, (2S)-(3'-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID, ... (5 entities in total) |
Functional Keywords | blood coagulation factor, serine proteinase, epidermal growth factor like domain |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P00742 P00742 |
Total number of polymer chains | 4 |
Total formula weight | 74878.83 |
Authors | Kamata, K.,Kim, S.H. (deposition date: 1998-03-19, release date: 1999-03-23, Last modification date: 2023-08-09) |
Primary citation | Kamata, K.,Kawamoto, H.,Honma, T.,Iwama, T.,Kim, S.H. Structural basis for chemical inhibition of human blood coagulation factor Xa. Proc.Natl.Acad.Sci.USA, 95:6630-6635, 1998 Cited by PubMed: 9618463DOI: 10.1073/pnas.95.12.6630 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report