1XH0

Structure of the N298S variant of human pancreatic alpha-amylase complexed with acarbose

1XH0 の概要

• エントリーDOI: 10.2210/pdb1xh0/pdb
• 関連するPDBエントリー: 1XGZ 1XH1 1XH2
• 分子名称: Alpha-amylase, pancreatic, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED HEXASACCHARIDE, ... (4 entities in total)
• 機能のキーワード: chloride amylase enzyme acarbose inhibitor, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 57095.38

構造登録者

Maurus, R.,Begum, A.,Kuo, H.H.,Racaza, A.,Numao, S.,Overall, C.M.,Withers, S.G.,Brayer, G.D. (登録日: 2004-09-17, 公開日: 2005-05-24, 最終更新日: 2023-10-25)

• 主引用文献: Maurus, R.,Begum, A.,Kuo, H.H.,Racaza, A.,Numao, S.,Andersen, C.,Tams, J.W.,Vind, J.,Overall, C.M.,Withers, S.G.,Brayer, G.D.; Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase; PROTEIN SCI., 14:743-755, 2005; PubMed: 15722449; DOI: 10.1110/ps.041079305

実験手法

X-RAY DIFFRACTION (2 Å)