1XD0

Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts

1XD0 の概要

• エントリーDOI: 10.2210/pdb1xd0/pdb
• 関連するPDBエントリー: 1XCW 1XCX 1XD1
• 分子名称: Alpha-amylase, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, ... (6 entities in total)
• 機能のキーワード: amylase, acarbose, acarbose analogues, inhibitor, acarviosine, isoacarbose, enzyme, catalysis, enzyme mechanism, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 57035.79

構造登録者

Li, C.,Begum, A.,Numao, S.,Park, K.H.,Withers, S.G.,Brayer, G.D. (登録日: 2004-09-03, 公開日: 2004-12-07, 最終更新日: 2020-07-29)

• 主引用文献: Li, C.,Begum, A.,Numao, S.,Park, K.H.,Withers, S.G.,Brayer, G.D.; Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts; Biochemistry, 44:3347-3357, 2005; PubMed: 15736945; DOI: 10.1021/10.1021/bi048334e

実験手法

X-RAY DIFFRACTION (2 Å)