1WVA

Crystal structure of human arginase I from twinned crystal

Summary for 1WVA

• Entry DOI: 10.2210/pdb1wva/pdb
• Related: 1WVB
• Descriptor: Arginase 1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE, ... (4 entities in total)
• Functional Keywords: hydrolase, twinned crystal, bec inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P05089
• Total number of polymer chains: 2
• Total formula weight: 70199.58

Authors

Di Costanzo, L.,Sabio, G.,Mora, A.,Rodriguez, P.C.,Ochoa, A.C.,Centeno, F.,Christianson, D.W. (deposition date: 2004-12-14, release date: 2005-09-06, Last modification date: 2023-10-25)

• Primary citation: Di Costanzo, L.,Sabio, G.,Mora, A.,Rodriguez, P.C.,Ochoa, A.C.,Centeno, F.,Christianson, D.W.; Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in the immune response; Proc.Natl.Acad.Sci.Usa, 102:13058-13063, 2005; PubMed: 16141327; DOI: 10.1073/pnas.0504027102

Experimental method

X-RAY DIFFRACTION (1.94 Å)