1WBO
fragment based p38 inhibitors
Summary for 1WBO
| Entry DOI | 10.2210/pdb1wbo/pdb |
| Related | 1A9U 1BL6 1BL7 1BMK 1DI9 1IAN 1KV1 1KV2 1M7Q 1OUK 1OUY 1OVE 1OZ1 1R39 1R3C 1W7H 1W82 1W83 1W84 1WBN 1WFC |
| Descriptor | MITOGEN-ACTIVATED PROTEIN KINASE 14, 2-CHLOROPHENOL (3 entities in total) |
| Functional Keywords | transferase, atp-binding, nuclear protein, phosphorylation, serine/threonine-protein kinase, 38 map kinase, inhibitor structure |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Cytoplasm (By similarity): Q16539 |
| Total number of polymer chains | 1 |
| Total formula weight | 41471.75 |
| Authors | Cleasby, A.,Devine, L.,Gill, A.,Jhoti, H. (deposition date: 2004-11-04, release date: 2005-01-27, Last modification date: 2011-07-13) |
| Primary citation | Hartshorn, M.J.,Murray, C.W.,Cleasby, A.,Frederickson, M.,Tickle, I.J.,Jhoti, H. Fragment-Based Lead Discovery Using X-Ray Crystallography J.Med.Chem., 48:403-, 2005 Cited by PubMed: 15658854DOI: 10.1021/JM0495778 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.16 Å) |
Structure validation
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