1W7H

p38 Kinase crystal structure in complex with small molecule inhibitor

Summary for 1W7H

Entry DOI	10.2210/pdb1w7h/pdb
Related	1A9U 1BL6 1BL7 1BMK 1DI9 1IAN 1KV1 1KV2 1M7Q 1OUK 1OUY 1OVE 1OZ1 1R39 1R3C 1W82 1W83 1W84 1WFC
Descriptor	MITOGEN-ACTIVATED PROTEIN KINASE 14, 3-(BENZYLOXY)PYRIDIN-2-AMINE (3 entities in total)
Functional Keywords	p38, kinase, inhibitor complex, phosphorylation, serine/threonine-protein kinase, transferase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm : Q16539
Total number of polymer chains	1
Total formula weight	41543.43
Authors	Jhoti, H.,Gill, A.,Cleasby, A.,Devine, L. (deposition date: 2004-09-02, release date: 2005-02-08, Last modification date: 2023-12-13)
Primary citation	Hartshorn, M.J.,Murray, C.W.,Cleasby, A.,Frederickson, M.,Tickle, I.J.,Jhoti, H. Fragment-Based Lead Discovery Using X-Ray Crystallography J.Med.Chem., 48:403-, 2005 Cited by PubMed: 15658854 DOI: 10.1021/JM0495778 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.214 Å)

Structure validation