1W21

Structure of Neuraminidase from English duck subtype N6 complexed with 30 mM sialic acid (NANA, Neu5Ac), crystal soaked for 43 hours at 291 K.

Summary for 1W21

• Entry DOI: 10.2210/pdb1w21/pdb
• Related: 1A14 1A4G 1A4Q 1B9S 1B9T 1B9V 1BJI 1E8T 1E8U 1E8V 1EUU 1F8B 1F8C 1F8D 1F8E 1INF 1ING 1INH 1INV 1INW 1INX 1INY 1IVB 1IVC 1IVD 1IVE 1IVF 1IVG 1KIT 1L7F 1L7G 1L7H 1MWE 1NCA 1NCB 1NCC 1NCD 1NMA 1NMB 1NMC 1NN2 1NNA 1NNB 1NNC 1NSB 1NSC 1NSD 1USR 1USX 1V0Z 1V2I 1V3B 1V3C 1V3D 1V3E 1VCJ 1W1X 1W20 1W8N 1W8O 1XOE 1XOG 1Z4V 1Z4W 1Z4X 1Z4Y 1Z4Z 1Z50 2BAT 2QWA 2QWB 2QWC 2QWD 2QWE 2QWF 2QWG 2QWH 2QWI 2QWJ 2QWK 2SIL 2SIM 3NN9 4NN9 5NN9 6NN9 7NN9
• Descriptor: NEURAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• Functional Keywords: influenza type a, neuraminidase, hb site, sialic acid, subtype n6, hydrolase
• Biological source: INFLUENZA A VIRUS
• Total number of polymer chains: 4
• Total formula weight: 180315.73

Authors

Rudino-Pinera, E.,Tunnah, P.,Crennell, S.J.,Webster, R.G.,Laver, W.G.,Garman, E.F. (deposition date: 2004-06-25, release date: 2006-01-25, Last modification date: 2023-12-13)

• Primary citation: Rudino-Pinera, E.,Tunnah, P.,Crennell, S.J.,Webster, R.G.,Laver, W.G.,Garman, E.F.; The Crystal Structure of Type a Influenza Virus Neuraminidase of the N6 Subtype Reveals the Existence of Two Separate Neu5Ac Binding Sites; To be Published,

Experimental method

X-RAY DIFFRACTION (2.08 Å)