Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1VGN

Structure-based design of the irreversible inhibitors to metallo--lactamase (IMP-1)

Summary for 1VGN
Entry DOI10.2210/pdb1vgn/pdb
DescriptorBeta-lactamase IMP-1, ZINC ION, 3-OXO-3-[(3-OXOPROPYL)SULFANYL]PROPANE-1-THIOLATE, ... (5 entities in total)
Functional Keywordsmetallo-beta-lactamase, zinc, irreversible inhibitor, hydrolase
Biological sourceSerratia marcescens
Total number of polymer chains2
Total formula weight50969.57
Authors
Kurosaki, H.,Yamaguchi, Y.,Higashi, T.,Soga, K.,Matsueda, S.,Misumi, S.,Yamagata, Y.,Arakawa, Y.,Goto, M. (deposition date: 2004-04-27, release date: 2005-06-21, Last modification date: 2023-10-25)
Primary citationKurosaki, H.,Yamaguchi, Y.,Higashi, T.,Soga, K.,Matsueda, S.,Yumoto, H.,Misumi, S.,Yamagata, Y.,Arakawa, Y.,Goto, M.
Irreversible Inhibition of Metallo-beta-lactamase (IMP-1) by 3-(3-Mercaptopropionylsulfanyl)propionic Acid Pentafluorophenyl Ester
Angew.Chem.Int.Ed.Engl., 44:3861-3864, 2005
Cited by
PubMed: 15892033
DOI: 10.1002/anie.200500835
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.63 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon