1VAR

MITOCHONDRIAL MANGANESE SUPEROXIDE DISMUTASE VARIANT WITH ILE 58 REPLACED BY THR

Summary for 1VAR

Entry DOI	10.2210/pdb1var/pdb
Descriptor	MANGANESE SUPEROXIDE DISMUTASE, MANGANESE (III) ION (3 entities in total)
Functional Keywords	oxidoreductase, manganese, mitochondrion, transit peptide, polymorphism
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion matrix: P04179
Total number of polymer chains	2
Total formula weight	44551.99
Authors	Borgstahl, G.E.O.,Parge, H.E.,Tainer, J.A. (deposition date: 1996-01-04, release date: 1996-06-10, Last modification date: 2024-02-14)
Primary citation	Borgstahl, G.E.,Parge, H.E.,Hickey, M.J.,Johnson, M.J.,Boissinot, M.,Hallewell, R.A.,Lepock, J.R.,Cabelli, D.E.,Tainer, J.A. Human mitochondrial manganese superoxide dismutase polymorphic variant Ile58Thr reduces activity by destabilizing the tetrameric interface. Biochemistry, 35:4287-4297, 1996 Cited by PubMed: 8605177 DOI: 10.1021/bi951892w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation