1V4G

Crystal Structure of gamma-Glutamylcysteine Synthetase from Escherichia coli B

Summary for 1V4G

Entry DOI	10.2210/pdb1v4g/pdb
Descriptor	Glutamate--cysteine ligase (2 entities in total)
Functional Keywords	glutathione regulation, beta barrel, peptide synthesis, ligase
Biological source	Escherichia coli
Total number of polymer chains	4
Total formula weight	233187.44
Authors	Hibi, T.,Nii, H.,Nakatsu, T.,Kato, H.,Hiratake, J.,Oda, J. (deposition date: 2003-11-13, release date: 2004-10-05, Last modification date: 2023-12-27)
Primary citation	Hibi, T.,Nii, H.,Nakatsu, T.,Kimura, A.,Kato, H.,Hiratake, J.,Oda, J. Crystal structure of gamma-glutamylcysteine synthetase: insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis PROC.NATL.ACAD.SCI.USA, 101:15052-15057, 2004 Cited by PubMed: 15477603 DOI: 10.1073/pnas.0403277101 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation