1V0O

Structure of P. falciparum PfPK5-Indirubin-5-sulphonate ligand complex

Summary for 1V0O

Entry DOI	10.2210/pdb1v0o/pdb
Related	1LCH 1OB3 1V0B
Descriptor	CELL DIVISION CONTROL PROTEIN 2 HOMOLOG, 2',3-DIOXO-1,1',2',3-TETRAHYDRO-2,3'-BIINDOLE-5'-SULFONIC ACID (3 entities in total)
Functional Keywords	transferase, serine/threonine-protein kinase, atp-binding, phosphorylation, cdk
Biological source	PLASMODIUM FALCIPARUM
Cellular location	Cytoplasm: Q07785
Total number of polymer chains	2
Total formula weight	66771.00
Authors	Holton, S.,Merckx, A.,Burgess, D.,Doerig, C.,Noble, M.,Endicott, J. (deposition date: 2004-03-31, release date: 2004-04-07, Last modification date: 2011-07-13)
Primary citation	Holton, S.,Merckx, A.,Burgess, D.,Doerig, C.,Noble, M.,Endicott, J. Structures of P. Falciparum Pfpk5 Test the Cdk Regulation Paradigm and Suggest Mechanisms of Small Molecule Inhibition Structure, 11:1329-, 2003 Cited by PubMed: 14604523 DOI: 10.1016/J.STR.2003.09.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation