Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1UWH

The complex of wild type B-RAF and BAY439006.

Summary for 1UWH
Entry DOI10.2210/pdb1uwh/pdb
Related1UWJ
DescriptorB-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE, 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, CHLORIDE ION, ... (4 entities in total)
Functional Keywordstransferase
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus : P15056
Total number of polymer chains2
Total formula weight63809.92
Authors
Barford, D.,Roe, S.M.,Wan, P.T.C.,Cancer Genome Project (deposition date: 2004-02-05, release date: 2004-03-19, Last modification date: 2023-12-13)
Primary citationWan, P.T.C.,Garnett, M.J.,Roe, S.M.,Lee, S.,Niculescu-Duvaz, D.,Good, V.M.,Jones, C.M.,Marshall, C.J.,Springer, C.J.,Barford, D.,Marais, R.
Mechanism of Activation of the Raf-Erk Signaling Pathway by Oncogenic Mutations of B-Raf
Cell(Cambridge,Mass.), 116:855-, 2004
Cited by
PubMed: 15035987
DOI: 10.1016/S0092-8674(04)00215-6
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.95 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon