1UWF

1.7 A resolution structure of the receptor binding domain of the FimH adhesin from uropathogenic E. coli

Summary for 1UWF

Entry DOI	10.2210/pdb1uwf/pdb
Related	1KIU 1KLF 1QUN
Descriptor	FIMH PROTEIN, butyl alpha-D-mannopyranoside, GLYCEROL, ... (4 entities in total)
Functional Keywords	bacterial adhesin, carbohydrate recognition, adherence to mammalian cells, ig-variable fold, cell adhesion
Biological source	ESCHERICHIA COLI
Cellular location	Fimbrium: P08191
Total number of polymer chains	1
Total formula weight	17245.18
Authors	Bouckaert, J.,Berglund, J.,Genst, E.D.,Cools, L.,Hung, C.-S.,Wuhrer, M.,Zavialov, A.,Langermann, S.,Hultgren, S.,Wyns, L.,Oscarson, S.,Knight, S.D.,De Greve, H. (deposition date: 2004-02-05, release date: 2005-02-16, Last modification date: 2023-12-13)
Primary citation	Bouckaert, J.,Berglund, J.,Schembri, M.,De Genst, E.,Cools, L.,Wuhrer, M.,Hung, C.,Pinkner, J.,Slattegard, R.,Zavialov, A.,Choudhury, D.,Langermann, S.,Hultgren, S.J.,Wyns, L.,Klemm, P.,Oscarson, S.,Knight, S.D.,De Greve, H. Receptor Binding Studies Disclose a Novel Class of High-Affinity Inhibitors of the Escherichia Coli Fimh Adhesin. Mol.Microbiol., 55:441-, 2005 Cited by PubMed: 15659162 DOI: 10.1111/J.1365-2958.2004.04415.X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.69 Å)

Structure validation