1UVT

BOVINE THROMBIN--BM14.1248 COMPLEX

Summary for 1UVT

• Entry DOI: 10.2210/pdb1uvt/pdb
• Descriptor: THROMBIN, N-{3-METHYL-5-[2-(PYRIDIN-4-YLAMINO)-ETHOXY]-PHENYL}-BENZENESULFONAMIDE, ... (4 entities in total)
• Functional Keywords: serine protease, hydrolase, thrombin, blood coagulation
• Biological source: Bos taurus (cattle); More
• Cellular location: Secreted, extracellular space: P00735 P00735
• Total number of polymer chains: 2
• Total formula weight: 35892.13

Authors

Engh, R.A.,Huber, R. (deposition date: 1996-10-16, release date: 1997-11-19, Last modification date: 2011-07-13)

• Primary citation: Engh, R.A.,Brandstetter, H.,Sucher, G.,Eichinger, A.,Baumann, U.,Bode, W.,Huber, R.,Poll, T.,Rudolph, R.,von der Saal, W.; Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design.; Structure, 4:1353-1362, 1996; PubMed: 8939759; DOI: 10.1016/S0969-2126(96)00142-6

Experimental method

X-RAY DIFFRACTION (2.5 Å)