1UPV

Crystal structure of the human Liver X receptor beta ligand binding domain in complex with a synthetic agonist

Summary for 1UPV

Entry DOI	10.2210/pdb1upv/pdb
Related	1P8D 1PQ6 1PQ9 1PQC 1UPW
Descriptor	OXYSTEROLS RECEPTOR LXR-BETA, N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE (3 entities in total)
Functional Keywords	receptor, nuclear hormone receptor, ligand binding domain, liver x receptor, transcription factor
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus : P55055
Total number of polymer chains	1
Total formula weight	29897.95
Authors	Hoerer, S.,Schmid, A.,Heckel, A.,Budzinski, R.M.,Nar, H. (deposition date: 2003-10-13, release date: 2004-10-20, Last modification date: 2023-12-13)
Primary citation	Hoerer, S.,Schmid, A.,Heckel, A.,Budzinski, R.M.,Nar, H. Crystal Structure of the Human Liver X Receptor Beta Ligand-Binding Domain in Complex with a Synthetic Agonist J.Mol.Biol., 334:853-, 2003 Cited by PubMed: 14643652 DOI: 10.1016/J.JMB.2003.10.033 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation