1UN5

ARH-II, AN ANGIOGENIN/RNASE A CHIMERA

Summary for 1UN5

Entry DOI	10.2210/pdb1un5/pdb
Related	1A4Y 1ANG 1AWZ 1B1E 1B1I 1B1J 1GV7 1H0D 1H52 1H53 1HBY 1K58 1K59 1K5A 1K5B 1UN3 1UN4 2ANG
Descriptor	ANGIOGENIN, CITRIC ACID (3 entities in total)
Functional Keywords	hydrolase, pancreatic ribonuclease, angiogenesis, angiogenin, chimera, hybrid, homolog scanning mutagenesis
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Secreted: P03950
Total number of polymer chains	1
Total formula weight	14649.55
Authors	Holloway, D.E.,Baker, M.D.,Acharya, K.R. (deposition date: 2003-09-04, release date: 2004-02-06, Last modification date: 2023-12-13)
Primary citation	Holloway, D.E.,Chavali, G.B.,Hares, M.C.,Baker, M.D.,Subbarao, G.V.,Shapiro, R.,Acharya, K.R. Crystallographic Studies on Structural Features that Determine the Enzymatic Specificity and Potency of Human Angiogenin: Thr44, Thr80 and Residues 38-41 Biochemistry, 43:1230-, 2004 Cited by PubMed: 14756559 DOI: 10.1021/BI035654+ PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation