1UMT

Stromelysin-1 catalytic domain with hydrophobic inhibitor bound, ph 7.0, 32oc, 20 mm cacl2, 15% acetonitrile; nmr average of 20 structures minimized with restraints

1UMT の概要

• エントリーDOI: 10.2210/pdb1umt/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000247
• 分子名称: STROMELYSIN-1, ZINC ION, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: zinc hydrolase, metzincin, matrix metalloproteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted, extracellular space, extracellular matrix (Probable): P08254
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20133.10

構造登録者

Van Doren, S.R.,Kurochkin, A.V.,Hu, W.,Zuiderweg, E.R.P. (登録日: 1995-10-31, 公開日: 1996-03-08, 最終更新日: 2012-12-12)

• 主引用文献: Van Doren, S.R.,Kurochkin, A.V.,Hu, W.,Ye, Q.Z.,Johnson, L.L.,Hupe, D.J.,Zuiderweg, E.R.; Solution structure of the catalytic domain of human stromelysin complexed with a hydrophobic inhibitor.; Protein Sci., 4:2487-2498, 1995; PubMed: 8580839

実験手法

SOLUTION NMR