1U9E

CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-397

Summary for 1U9E

Entry DOI	10.2210/pdb1u9e/pdb
Related	1U3Q 1U3R 1U3S
Descriptor	Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1, 2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL, ... (4 entities in total)
Functional Keywords	estrogen receptor, estrogen receptor beta, er-beta, er, estrogen, nuclear receptor, transcription factor, agonist, transcription
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: Q92731
Total number of polymer chains	4
Total formula weight	57019.60
Authors	Manas, E.S.,Unwalla, R.J.,Xu, Z.B.,Malamas, M.S.,Miller, C.P.,Harris, H.A.,Hsiao, C.,Akopian, T.,Hum, W.T.,Malakian, K.,Wolfrom, S.,Bapat, A.,Bhat, R.A.,Stahl, M.L.,Somers, W.S.,Alvarez, J.C. (deposition date: 2004-08-09, release date: 2005-03-01, Last modification date: 2024-04-03)
Primary citation	Manas, E.S.,Unwalla, R.J.,Xu, Z.B.,Malamas, M.S.,Miller, C.P.,Harris, H.A.,Hsiao, C.,Akopian, T.,Hum, W.T.,Malakian, K.,Wolfrom, S.,Bapat, A.,Bhat, R.A.,Stahl, M.L.,Somers, W.S.,Alvarez, J.C. Structure-Based Design Of Estrogen Receptor-beta Selective Ligands J.Am.Chem.Soc., 126:15106-15119, 2004 Cited by PubMed: 15548008 DOI: 10.1021/ja047633o PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation