1U54

Crystal Structures of the Phosphorylated and Unphosphorylated Kinase Domains of the CDC42-associated Tyrosine Kinase ACK1 bound to AMP-PCP

Summary for 1U54

Entry DOI	10.2210/pdb1u54/pdb
Descriptor	Activated CDC42 kinase 1, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (5 entities in total)
Functional Keywords	tyrosine kinase, transferase
Biological source	Homo sapiens (human) More
Cellular location	Cell membrane: Q07912 Q07912
Total number of polymer chains	2
Total formula weight	67303.71
Authors	Lougheed, J.C.,Chen, R.H.,Mak, P.,Stout, T.J. (deposition date: 2004-07-26, release date: 2004-08-31, Last modification date: 2023-11-15)
Primary citation	Lougheed, J.C.,Chen, R.H.,Mak, P.,Stout, T.J. Crystal Structures of the Phosphorylated and Unphosphorylated Kinase Domains of the Cdc42-associated Tyrosine Kinase ACK1. J.Biol.Chem., 279:44039-44045, 2004 Cited by PubMed: 15308621 DOI: 10.1074/jbc.M406703200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation