1U27

Triglycine variant of the ARNO Pleckstrin Homology Domain in complex with Ins(1,3,4,5)P4

Summary for 1U27

Entry DOI	10.2210/pdb1u27/pdb
Descriptor	Cytohesin 2, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE (3 entities in total)
Functional Keywords	pleckstrin homology domain, lipid binding, phosphoinositide, lipid binding protein
Biological source	Mus musculus (house mouse)
Cellular location	Cell membrane (By similarity): P63034
Total number of polymer chains	1
Total formula weight	15554.15
Authors	Cronin, T.C.,DiNitto, J.P.,Czech, M.P.,Lambright, D.G. (deposition date: 2004-07-16, release date: 2005-02-01, Last modification date: 2023-08-23)
Primary citation	Cronin, T.C.,DiNitto, J.P.,Czech, M.P.,Lambright, D.G. Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains Embo J., 23:3711-3720, 2004 Cited by PubMed: 15359279 DOI: 10.1038/sj.emboj.7600388 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation