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1U21

transthyretin with tethered inhibitor on one monomer.

Summary for 1U21
Entry DOI10.2210/pdb1u21/pdb
DescriptorTransthyretin, 2-[(3,5-DICHLORO-4-TRIOXIDANYLPHENYL)AMINO]BENZOIC ACID (3 entities in total)
Functional Keywordstransthyretin, amyloid, hormone-growth factor complex, hormone/growth factor
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P02766
Total number of polymer chains2
Total formula weight28214.96
Authors
Wiseman, R.L.,Johnson, S.M.,Kelker, M.S.,Foss, T.,Wilson, I.A.,Kelly, J.W. (deposition date: 2004-07-16, release date: 2005-06-28, Last modification date: 2023-08-23)
Primary citationWiseman, R.L.,Johnson, S.M.,Kelker, M.S.,Foss, T.,Wilson, I.A.,Kelly, J.W.
Kinetic stabilization of an oligomeric protein by a single ligand binding event
J.Am.Chem.Soc., 127:5540-5551, 2005
Cited by
PubMed: 15826192
DOI: 10.1021/ja042929f
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.69 Å)
Structure validation

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