1TX8

Bovine Trypsin complexed with AMSO

Summary for 1TX8

Entry DOI	10.2210/pdb1tx8/pdb
Related	1TX7
Descriptor	Trypsinogen, CALCIUM ION, 4-(METHYLSULFONYL)BENZENECARBOXIMIDAMIDE, ... (4 entities in total)
Functional Keywords	trypsin, hydrolase
Biological source	Bos taurus (cattle)
Cellular location	Secreted, extracellular space: P00760
Total number of polymer chains	1
Total formula weight	23562.61
Authors	Mesecar, A.D. (deposition date: 2004-07-02, release date: 2005-10-18, Last modification date: 2023-08-23)
Primary citation	Rumthao, S.,Lee, O.,Sheng, Q.,Fu, W.,Mulhearn, D.C.,Crich, D.,Mesecar, A.D.,Johnson, M.E. Design, synthesis, and evaluation of oxyanion-hole selective inhibitor substituents for the S1 subsite of factor Xa Bioorg.Med.Chem.Lett., 14:5165-5170, 2004 Cited by PubMed: 15380220 DOI: 10.1016/j.bmcl.2004.07.054 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation