1TV5
Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor
Summary for 1TV5
Entry DOI | 10.2210/pdb1tv5/pdb |
Descriptor | Dihydroorotate dehydrogenase homolog, mitochondrial, SULFATE ION, (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide, ... (7 entities in total) |
Functional Keywords | alpha-beta barrel; tim barrel, oxidoreductase |
Biological source | Plasmodium falciparum (malaria parasite P. falciparum) |
Cellular location | Mitochondrion inner membrane (By similarity); Single-pass membrane protein (Potential): Q08210 |
Total number of polymer chains | 1 |
Total formula weight | 51939.95 |
Authors | Hurt, D.E.,Widom, J.,Clardy, J. (deposition date: 2004-06-27, release date: 2005-09-06, Last modification date: 2023-08-23) |
Primary citation | Hurt, D.E.,Widom, J.,Clardy, J. Structure of Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor. Acta Crystallogr.,Sect.D, 62:312-323, 2006 Cited by PubMed: 16510978DOI: 10.1107/S0907444905042642 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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