1TSH

TERTIARY STRUCTURES OF THREE AMYLOIDOGENIC TRANSTHYRETIN VARIANTS AND IMPLICATIONS FOR AMYLOID FIBRIL FORMATION

Summary for 1TSH

Entry DOI	10.2210/pdb1tsh/pdb
Descriptor	TRANSTHYRETIN (2 entities in total)
Functional Keywords	thyroid hormone, liver, plasma, cerebrospinal fluid, polyneuropathy, disease mutation, transport, thyroxine
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02766
Total number of polymer chains	2
Total formula weight	27494.67
Authors	Schormann, N.,Murrell, J.R.,Benson, M.D. (deposition date: 1996-10-16, release date: 1997-04-21, Last modification date: 2023-08-09)
Primary citation	Schormann, N.,Murrell, J.R.,Benson, M.D. Tertiary structures of amyloidogenic and non-amyloidogenic transthyretin variants: new model for amyloid fibril formation. Amyloid, 5:175-187, 1998 Cited by PubMed: 9818054 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation