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1TQB

Ovine recombinant PrP(114-234), VRQ variant in complex with the Fab of the VRQ14 antibody

Summary for 1TQB
Entry DOI10.2210/pdb1tqb/pdb
Related1TQC
Descriptorprion protein, VRQ14 Fab Heavy chain, VRQ14 Fab light chain, ... (4 entities in total)
Functional Keywordsprion, antibody, unknown function-immune system complex, unknown function/immune system
Biological sourceOvis aries (sheep)
More
Cellular locationCell membrane; Lipid-anchor, GPI-anchor: P23907
Total number of polymer chains3
Total formula weight59162.88
Authors
Eghiaian, F.,Grosclaude, J.,Debey, P.,Doublet, B.,Treguer, E.,Rezaei, H.,Knossow, M. (deposition date: 2004-06-17, release date: 2004-07-06, Last modification date: 2011-07-13)
Primary citationEghiaian, F.,Grosclaude, J.,Lesceu, S.,Debey, P.,Doublet, B.,Treguer, E.,Rezaei, H.,Knossow, M.
Insight into the PrPC-->PrPSc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants
Proc.Natl.Acad.Sci.USA, 101:10254-10259, 2004
Cited by
PubMed: 15240887
DOI: 10.1073/pnas.0400014101
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.55 Å)
Structure validation

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