1TOH

TYROSINE HYDROXYLASE CATALYTIC AND TETRAMERIZATION DOMAINS FROM RAT

Summary for 1TOH

Entry DOI	10.2210/pdb1toh/pdb
Descriptor	TYROSINE HYDROXYLASE, FE (III) ION (3 entities in total)
Functional Keywords	hydroxylase, neurotransmitter biosynthesis, non-heme iron, pterin co-substrate
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	1
Total formula weight	39329.93
Authors	Goodwill, K.E.,Sabatier, C.,Stevens, R.C. (deposition date: 1997-06-04, release date: 1998-06-03, Last modification date: 2024-02-14)
Primary citation	Goodwill, K.E.,Sabatier, C.,Marks, C.,Raag, R.,Fitzpatrick, P.F.,Stevens, R.C. Crystal structure of tyrosine hydroxylase at 2.3 A and its implications for inherited neurodegenerative diseases. Nat.Struct.Biol., 4:578-585, 1997 Cited by PubMed: 9228951 DOI: 10.1038/nsb0797-578 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation