1TMT

CHANGES IN INTERACTIONS IN COMPLEXES OF HIRUDIN DERIVATIVES AND HUMAN ALPHA-THROMBIN DUE TO DIFFERENT CRYSTAL FORMS

1TMT の概要

• エントリーDOI: 10.2210/pdb1tmt/pdb
• 関連するBIRD辞書のPRD_ID: PRD_001148
• 分子名称: ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), CGP 50,856 INHIBITOR, cleaved N-terminal tripeptide fragment, d-Phe-Pro-Arg, ... (6 entities in total)
• 機能のキーワード: complex, serine protease, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 36426.39

構造登録者

Priestle, J.P.,Gruetter, M.G. (登録日: 1994-05-26, 公開日: 1994-09-30, 最終更新日: 2022-12-21)

• 主引用文献: Priestle, J.P.,Rahuel, J.,Rink, H.,Tones, M.,Grutter, M.G.; Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms.; Protein Sci., 2:1630-1642, 1993; PubMed: 8251938

実験手法

X-RAY DIFFRACTION (2.2 Å)