1TM5

crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59A mutant

Summary for 1TM5

Entry DOI	10.2210/pdb1tm5/pdb
Related	1tm1 1tm3 1tm4 1tm7 1tmg 1to1 1to2
Descriptor	Subtilisin BPN', chymotrypsin inhibitor 2, CALCIUM ION, ... (7 entities in total)
Functional Keywords	serine protease, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bacillus amyloliquefaciens More
Cellular location	Secreted: P00782
Total number of polymer chains	2
Total formula weight	36959.15
Authors	Radisky, E.S.,Kwan, G.,Karen Lu, C.J.,Koshland Jr., D.E. (deposition date: 2004-06-10, release date: 2004-11-09, Last modification date: 2023-08-23)
Primary citation	Radisky, E.S.,Kwan, G.,Karen Lu, C.J.,Koshland Jr., D.E. Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,). Biochemistry, 43:13648-13656, 2004 Cited by PubMed: 15504027 DOI: 10.1021/bi048797k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation