1TH1

Beta-catenin in complex with a phosphorylated APC 20aa repeat fragment

Summary for 1TH1

Entry DOI	10.2210/pdb1th1/pdb
Descriptor	Beta-catenin, Adenomatous polyposis coli protein (3 entities in total)
Functional Keywords	protein-protein complex, cell adhesion-antitumor protein complex, cell adhesion/antitumor protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: P35222 Cell junction, adherens junction: P25054
Total number of polymer chains	4
Total formula weight	155244.70
Authors	Xing, Y.,Clements, W.K.,Le Trong, I.,Hinds, T.R.,Stenkamp, R.,Kimelman, D.,Xu, W. (deposition date: 2004-05-31, release date: 2004-09-07, Last modification date: 2023-08-23)
Primary citation	Xing, Y.,Clements, W.K.,Le Trong, I.,Hinds, T.R.,Stenkamp, R.,Kimelman, D.,Xu, W. Crystal Structure of a beta-Catenin/APC Complex Reveals a Critical Role for APC Phosphorylation in APC Function. Mol.Cell, 15:523-533, 2004 Cited by PubMed: 15327769 DOI: 10.1016/j.molcel.2004.08.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation