1TFX

COMPLEX OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR WITH PORCINE TRYPSIN

1TFX の概要

• エントリーDOI: 10.2210/pdb1tfx/pdb
• 分子名称: TRYPSIN, TISSUE FACTOR PATHWAY INHIBITOR, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: complex (serine protease-inhibitor), hydrolase, inhibitor, blood coagulation, complex (serine protease-inhibitor) complex, complex (serine protease/inhibitor)
• 由来する生物種: Sus scrofa (pig); 詳細
• 細胞内の位置: Secreted, extracellular space: P00761; Secreted: P10646
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 60774.48

構造登録者

Stubbs, M.T.,Huber, R. (登録日: 1997-01-21, 公開日: 1998-01-21, 最終更新日: 2023-08-09)

• 主引用文献: Burgering, M.J.,Orbons, L.P.,van der Doelen, A.,Mulders, J.,Theunissen, H.J.,Grootenhuis, P.D.,Bode, W.,Huber, R.,Stubbs, M.T.; The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa.; J.Mol.Biol., 269:395-407, 1997; PubMed: 9199408; DOI: 10.1006/jmbi.1997.1029

実験手法

X-RAY DIFFRACTION (2.6 Å)