Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1T69

Crystal Structure of human HDAC8 complexed with SAHA

Summary for 1T69
Entry DOI10.2210/pdb1t69/pdb
Related1T64 1T67
DescriptorHistone deacetylase 8, ZINC ION, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE (3 entities in total)
Functional Keywordshistone deacetylase, zinc hydrolase, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationNucleus: Q9BY41
Total number of polymer chains1
Total formula weight42132.21
Authors
Primary citationSomoza, J.R.,Skene, R.J.,Katz, B.A.,Mol, C.,Ho, J.D.,Jennings, A.J.,Luong, C.,Arvai, A.,Buggy, J.J.,Chi, E.,Tang, J.,Sang, B.-C.,Verner, E.,Wynands, R.,Leahy, E.M.,Dougan, D.R.,Snell, G.,Navre, M.,Knuth, M.W.,Swanson, R.V.,McRee, D.E.,Tari, L.W.
Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases
Structure, 12:1325-1334, 2004
Cited by
PubMed: 15242608
DOI: 10.1016/j.str.2004.04.012
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.91 Å)
Structure validation

217157

PDB entries from 2024-03-13

PDB statisticsPDBj update infoContact PDBjnumon