1T63

Crystal Structure of the Androgen Receptor Ligand Binding Domain with DHT and a peptide derived from its physiological coactivator GRIP1 NR box3

Summary for 1T63

• Entry DOI: 10.2210/pdb1t63/pdb
• Related: 1T5Z 1T65
• Descriptor: Androgen receptor, Nuclear receptor coactivator 2, 5-ALPHA-DIHYDROTESTOSTERONE, ... (4 entities in total)
• Functional Keywords: androgen receptor ligand binding domain grip1 nr boxes coactivators dht crystal structure, hormone-growth factor complex, hormone/growth factor
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : P10275 Q15596
• Total number of polymer chains: 2
• Total formula weight: 31276.71

Authors

Estebanez-Perpina, E.,Moore, J.M.R.,Mar, E.,Nguyen, P.,Delgado-Rodrigues, E.,Baxter, J.D.,Webb, P.,Fletterick, R.J.,Guy, R.K. (deposition date: 2004-05-05, release date: 2005-01-25, Last modification date: 2024-02-14)

• Primary citation: Estebanez-Perpina, E.,Moore, J.M.R.,Mar, E.,Delgado-Rodrigues, E.,Nguyen, P.,Baxter, J.D.,Buehrer, B.M.,Webb, P.,Fletterick, R.J.,Guy, R.K.; The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor.; J.Biol.Chem., 280:8060-8068, 2005; PubMed: 15563469; DOI: 10.1074/jbc.M407046200

Experimental method

X-RAY DIFFRACTION (2.07 Å)