1T39

HUMAN O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE COVALENTLY CROSSLINKED TO DNA

Summary for 1T39

• Entry DOI: 10.2210/pdb1t39/pdb
• Related: 1EH6 1EH7 1EH8 1T38
• Descriptor: 5'-D(*GP*CP*CP*AP*TP*GP*(E1X)P*CP*TP*AP*GP*TP*A)-3', 5'-D(*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3', Methylated-DNA--protein-cysteine methyltransferase (3 entities in total)
• Functional Keywords: alkyltransferase, methyltransferase, dna repair, helix-turn-helix, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P16455
• Total number of polymer chains: 6
• Total formula weight: 56655.41

Authors

Daniels, D.S.,Woo, T.T.,Luu, K.X.,Noll, D.M.,Clarke, N.D.,Pegg, A.E.,Tainer, J.A. (deposition date: 2004-04-25, release date: 2004-07-13, Last modification date: 2023-08-23)

• Primary citation: Daniels, D.S.,Woo, T.T.,Luu, K.X.,Noll, D.M.,Clarke, N.D.,Pegg, A.E.,Tainer, J.A.; DNA binding and nucleotide flipping by the human DNA repair protein AGT.; Nat.Struct.Mol.Biol., 11:714-720, 2004; PubMed: 15221026; DOI: 10.1038/nsmb791

Experimental method

X-RAY DIFFRACTION (3.3 Å)