1SR7

Progesterone Receptor Hormone Binding Domain with Bound Mometasone Furoate

Summary for 1SR7

Entry DOI	10.2210/pdb1sr7/pdb
Related	1A28 1E3K 1SQN
Descriptor	Progesterone receptor, MOMETASONE FUROATE, SULFATE ION, ... (5 entities in total)
Functional Keywords	progesterone receptor, mometasone, progesterone, nuclear receptor, hormone receptor, transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus. Isoform A: Nucleus: P06401
Total number of polymer chains	2
Total formula weight	60822.76
Authors	Madauss, K.P.,Deng, S.-J.,Austin, R.J.,Lambert, M.H.,McLay, I.,Pritchard, J.,Short, S.A.,Stewart, E.L.,Uings, I.J.,Williams, S.P. (deposition date: 2004-03-22, release date: 2004-06-22, Last modification date: 2023-08-23)
Primary citation	Madauss, K.P.,Deng, S.-J.,Austin, R.J.,Lambert, M.H.,McLay, I.,Pritchard, J.,Short, S.A.,Stewart, E.L.,Uings, I.J.,Williams, S.P. Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes J.Med.Chem., 47:3381-3387, 2004 Cited by PubMed: 15189034 DOI: 10.1021/jm030640n PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.46 Å)

Structure validation