1SPS

BINDING OF A HIGH AFFINITY PHOSPHOTYROSYL PEPTIDE TO THE SRC SH2 DOMAIN: CRYSTAL STRUCTURES OF THE COMPLEXED AND PEPTIDE-FREE FORMS

Summary for 1SPS

Entry DOI	10.2210/pdb1sps/pdb
Descriptor	SRC SH2 DOMAIN, PEPTIDE YEEI (3 entities in total)
Functional Keywords	transferase(phosphotransferase)
Biological source	Rous sarcoma virus More
Cellular location	Host membrane; Single-pass membrane protein (Potential): P03079
Total number of polymer chains	6
Total formula weight	40331.99
Authors	Waksman, G.,Kuriyan, J. (deposition date: 1993-03-05, release date: 1994-05-31, Last modification date: 2011-07-13)
Primary citation	Waksman, G.,Shoelson, S.E.,Pant, N.,Cowburn, D.,Kuriyan, J. Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms. Cell(Cambridge,Mass.), 72:779-790, 1993 Cited by PubMed: 7680960 DOI: 10.1016/0092-8674(93)90405-F PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation