1SOM

TORPEDO CALIFORNICA ACETYLCHOLINESTERASE INHIBITED BY NERVE AGENT GD (SOMAN).

Summary for 1SOM

Entry DOI	10.2210/pdb1som/pdb
Descriptor	PROTEIN (ACETYLCHOLINESTERASE), 2-acetamido-2-deoxy-beta-D-glucopyranose, UNKNOWN ATOM OR ION, ... (5 entities in total)
Functional Keywords	serine hydrolase, cholinesterase, nerve agent, organophosphorous acid anhydride
Biological source	Torpedo californica (Pacific electric ray)
Cellular location	Isoform H: Cell membrane; Lipid-anchor, GPI- anchor. Isoform T: Cell membrane; Peripheral membrane protein: P04058
Total number of polymer chains	1
Total formula weight	61846.52
Authors	Greenblatt, H.M.,Millard, C.B.,Sussman, J.L.,Silman, I. (deposition date: 1999-03-17, release date: 1999-06-25, Last modification date: 2023-08-23)
Primary citation	Millard, C.B.,Kryger, G.,Ordentlich, A.,Greenblatt, H.M.,Harel, M.,Raves, M.L.,Segall, Y.,Barak, D.,Shafferman, A.,Silman, I.,Sussman, J.L. Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level. Biochemistry, 38:7032-7039, 1999 Cited by PubMed: 10353814 DOI: 10.1021/bi982678l PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation