1SMI

A single mutation of P450 BM3 induces the conformational rearrangement seen upon substrate-binding in wild-type enzyme

Summary for 1SMI

Entry DOI	10.2210/pdb1smi/pdb
Related	1BU7 1FAG 1JPZ 1SMJ
Descriptor	Bifunctional P-450:NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywords	monooxygenase; fatty acid oxygenase; cytochrome p450; substrate binding, oxidoreductase
Biological source	Bacillus megaterium
Cellular location	Cytoplasm (By similarity): P14779
Total number of polymer chains	2
Total formula weight	108941.63
Authors	Joyce, M.G.,Girvan, H.M.,Munro, A.W.,Leys, D. (deposition date: 2004-03-09, release date: 2004-06-08, Last modification date: 2023-08-23)
Primary citation	Joyce, M.G.,Girvan, H.M.,Munro, A.W.,Leys, D. A Single Mutation in Cytochrome P450 BM3 Induces the Conformational Rearrangement Seen upon Substrate Binding in the Wild-type Enzyme J.Biol.Chem., 279:23287-23293, 2004 Cited by PubMed: 15020590 DOI: 10.1074/jbc.M401717200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation