1SLW

RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; NICKEL-BOUND

Summary for 1SLW

Entry DOI	10.2210/pdb1slw/pdb
Descriptor	ECOTIN, ANIONIC TRYPSIN, CALCIUM ION, ... (6 entities in total)
Functional Keywords	serine protease, inhibitor, complex, metal binding sites, protein engineering, protease-substrate interactions, metalloproteins, complex (serine protease-inhibitor) complex, complex (serine protease/inhibitor)
Biological source	Escherichia coli More
Cellular location	Periplasm: P23827 Secreted, extracellular space: P00763
Total number of polymer chains	2
Total formula weight	40207.33
Authors	Brinen, L.S.,Fletterick, R.J. (deposition date: 1996-02-07, release date: 1996-07-11, Last modification date: 2021-11-03)
Primary citation	Brinen, L.S.,Willett, W.S.,Craik, C.S.,Fletterick, R.J. X-ray structures of a designed binding site in trypsin show metal-dependent geometry. Biochemistry, 35:5999-6009, 1996 Cited by PubMed: 8634241 DOI: 10.1021/bi9530200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation