1SIX

Mycobacterium tuberculosis dUTPase complexed with magnesium and alpha,beta-imido-dUTP

Summary for 1SIX

Entry DOI	10.2210/pdb1six/pdb
Related	1MQ7
Descriptor	Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywords	jelly-roll, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, hydrolase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	18605.92
Authors	Sawaya, M.R.,Chan, S.,Segelke, B.,Lekin, T.,Krupka, H.,Cho, U.-S.,Kim, M.,So, M.,Kim, C.-Y.,Naranjo, C.M.,Rogers, Y.C.,Park, M.S.,Waldo, G.S.,Pashkov, I.,Cascio, D.,Yeates, T.O.,Perry, J.L.,Terwilliger, T.C.,Eisenberg, D.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2004-03-01, release date: 2004-03-09, Last modification date: 2023-08-23)
Primary citation	Chan, S.,Segelke, B.,Lekin, T.,Krupka, H.,Cho, U.S.,Kim, M.-Y.,So, M.,Kim, C.-Y.,Naranjo, C.M.,Rogers, Y.C.,Park, M.S.,Waldo, G.S.,Pashkov, I.,Cascio, D.,Perry, J.L.,Sawaya, M.R. Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism. J.Mol.Biol., 341:503-517, 2004 Cited by PubMed: 15276840 DOI: 10.1016/j.jmb.2004.06.028 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation