1SHR

Crystal structure of ferrocyanide bound human hemoglobin A2 at 1.88A resolution

1SHR の概要

• エントリーDOI: 10.2210/pdb1shr/pdb
• 関連するPDBエントリー: 1SI4
• 分子名称: Hemoglobin alpha chain, Hemoglobin delta chain, CYANIDE ION, ... (6 entities in total)
• 機能のキーワード: hemoglobin a2, ferrocyanide binding, oxygen transport, beta-thalassemia, oxygen storage-transport complex, oxygen storage/transport
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 65086.90

構造登録者

Sen, U.,Dasgupta, J.,Choudhury, D.,Datta, P.,Chakrabarti, A.,Chakrabarty, S.B.,Chakrabarty, A.,Dattagupta, J.K. (登録日: 2004-02-26, 公開日: 2004-10-26, 最終更新日: 2023-10-25)

• 主引用文献: Sen, U.,Dasgupta, J.,Choudhury, D.,Datta, P.,Chakrabarti, A.,Chakrabarty, S.B.,Chakrabarty, A.,Dattagupta, J.K.; Crystal structures of HbA2 and HbE and modeling of hemoglobin delta4: interpretation of the thermal stability and the antisickling effect of HbA2 and identification of the ferrocyanide binding site in Hb; Biochemistry, 43:12477-12488, 2004; PubMed: 15449937; DOI: 10.1021/bi048903i

実験手法

X-RAY DIFFRACTION (1.88 Å)