1SF1

NMR STRUCTURE OF HUMAN INSULIN under Amyloidogenic Condition, 15 STRUCTURES

Summary for 1SF1

• Entry DOI: 10.2210/pdb1sf1/pdb
• Related: 2HIU
• Descriptor: INSULIN A CHAIN, Insulin (2 entities in total)
• Functional Keywords: hormone, human insulin, hormone-growth factor complex, hormone/growth factor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01308 P01308
• Total number of polymer chains: 2
• Total formula weight: 5817.65

Authors

Weiss, M.A.,Hua, Q.X. (deposition date: 2004-02-19, release date: 2004-03-30, Last modification date: 2022-03-02)

• Primary citation: Hua, Q.X.,Weiss, M.A.; Mechanism of insulin fibrillation: the structure of insulin under amyloidogenic conditions resembles a protein-folding intermediate; J.Biol.Chem., 279:21449-21460, 2004; PubMed: 14988398; DOI: 10.1074/jbc.M314141200

Experimental method

SOLUTION NMR