1S70
Complex between protein ser/thr phosphatase-1 (delta) and the myosin phosphatase targeting subunit 1 (MYPT1)
Summary for 1S70
| Entry DOI | 10.2210/pdb1s70/pdb |
| Related | 1FJM 1IT6 1JK7 |
| Descriptor | Serine/threonine protein phosphatase PP1-beta (or delta) catalytic subunit, 130 kDa myosin-binding subunit of smooth muscle myosin phophatase (M130), MANGANESE (II) ION, ... (5 entities in total) |
| Functional Keywords | myosin phosphatase, mypt1, pp1, myosin regulation, deposphorylation, hydrolase |
| Biological source | Homo sapiens (human) More |
| Cellular location | Cytoplasm: P62140 |
| Total number of polymer chains | 2 |
| Total formula weight | 71121.58 |
| Authors | Kerff, F.,Terrak, M.,Dominguez, R. (deposition date: 2004-01-28, release date: 2004-06-22, Last modification date: 2023-08-23) |
| Primary citation | Terrak, M.,Kerff, F.,Langsetmo, K.,Tao, T.,Dominguez, R. Structural basis of protein phosphatase 1 regulation Nature, 429:780-784, 2004 Cited by PubMed: 15164081DOI: 10.1038/nature02582 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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