1RZG

Crystal structure of Human anti-HIV-1 GP120 reactive antibody 412d

Summary for 1RZG

Entry DOI	10.2210/pdb1rzg/pdb
Related	1RZ7 1RZ8 1RZF 1RZI 1RZJ 1RZK
Related PRD ID	PRD_900003
Descriptor	Fab 412d light chain, Fab 412d heavy chain, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... (6 entities in total)
Functional Keywords	hiv-1; gp120; cd4i; antibodies; tyrosine sulfation; vh-gene usage, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	99135.71
Authors	Huang, C.C.,Venturi, M.,Majeed, S.,Moore, M.J.,Phogat, S.,Zhang, M.-Y.,Dimitrov, D.S.,Hendrickson, W.A.,Robinson, J.,Sodroski, J.,Wyatt, R.,Choe, H.,Farzan, M.,Kwong, P.D. (deposition date: 2003-12-24, release date: 2004-02-03, Last modification date: 2023-12-13)
Primary citation	Huang, C.C.,Venturi, M.,Majeed, S.,Moore, M.J.,Phogat, S.,Zhang, M.-Y.,Dimitrov, D.S.,Hendrickson, W.A.,Robinson, J.,Sodroski, J.,Wyatt, R.,Choe, H.,Farzan, M.,Kwong, P.D. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101:2706-2711, 2004 Cited by PubMed: 14981267 DOI: 10.1073/pnas.0308527100 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation