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1RX7

STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE

Summary for 1RX7
Entry DOI10.2210/pdb1rx7/pdb
DescriptorDIHYDROFOLATE REDUCTASE, FOLIC ACID (3 entities in total)
Functional Keywordsoxidoreductase, nadp, trimethoprim resistance, methotrexate resistance, one-carbon metabolism
Biological sourceEscherichia coli
Total number of polymer chains1
Total formula weight18461.72
Authors
Sawaya, M.R. (deposition date: 1996-10-25, release date: 1997-03-12, Last modification date: 2023-08-09)
Primary citationSawaya, M.R.,Kraut, J.
Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36:586-603, 1997
Cited by
PubMed: 9012674
DOI: 10.1021/bi962337c
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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