1RTD

STRUCTURE OF A CATALYTIC COMPLEX OF HIV-1 REVERSE TRANSCRIPTASE: IMPLICATIONS FOR NUCLEOSIDE ANALOG DRUG RESISTANCE

Summary for 1RTD

Entry DOI	10.2210/pdb1rtd/pdb
Descriptor	DNA TEMPLATE FOR REVERSE TRANSCRIPTASE, DNA PRIMER FOR REVERSE TRANSCRIPTASE, PROTEIN (REVERSE TRANSCRIPTASE), ... (6 entities in total)
Functional Keywords	complex(nucleotidyltransferase, dna, dntp), protein/dna, transferase-dna complex, transferase/dna
Biological source	Human immunodeficiency virus 1 More
Cellular location	Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03366 P04585
Total number of polymer chains	8
Total formula weight	261133.52
Authors	Chopra, R.,Huang, H.,Verdine, G.L.,Harrison, S.C. (deposition date: 1998-08-26, release date: 1998-12-09, Last modification date: 2024-02-14)
Primary citation	Huang, H.,Chopra, R.,Verdine, G.L.,Harrison, S.C. Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance. Science, 282:1669-1675, 1998 Cited by PubMed: 9831551 DOI: 10.1126/science.282.5394.1669 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation