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1RSZ

Structure of human purine nucleoside phosphorylase in complex with DADMe-Immucillin-H and sulfate

Summary for 1RSZ
Entry DOI10.2210/pdb1rsz/pdb
Related1RR6 1RT9
DescriptorPurine nucleoside phosphorylase, SULFATE ION, 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, ... (4 entities in total)
Functional Keywordspnp, transition-state analogue, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight32738.35
Authors
Shi, W.,Lewandowicz, A.,Tyler, P.C.,Furneaux, R.H.,Almo, S.C.,Schramm, V.L. (deposition date: 2003-12-10, release date: 2005-02-22, Last modification date: 2023-08-23)
Primary citationShi, W.,Lewandowicz, A.,Tyler, P.C.,Furneaux, R.H.,Almo, S.C.,Schramm, V.L.
Structural comparison of human and malarial purine nucleoside phosphorylases
To be Published,
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217705

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