1RK3

crystal structure of the rat vitamin D receptor ligand binding domain complexed with 1,25-dihydroxyvitamin D3 and a synthetic peptide containing the NR2 box of DRIP 205

Summary for 1RK3

Entry DOI	10.2210/pdb1rk3/pdb
Related	1RJK 1RKG 1RKH
Descriptor	Vitamin D3 receptor, Peroxisome proliferator-activated receptor binding protein, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, ... (4 entities in total)
Functional Keywords	nuclear receptor-ligand complex, nuclear receptor-coactivator interactions, hormone-growth factor receptor complex, hormone/growth factor receptor
Biological source	Rattus norvegicus (Norway rat)
Cellular location	Nucleus: P13053 Q15648
Total number of polymer chains	2
Total formula weight	34971.26
Authors	Vanhooke, J.L.,M Benning, M.,Bauer, C.B.,Pike, J.W.,DeLuca, H.F. (deposition date: 2003-11-20, release date: 2004-04-13, Last modification date: 2023-08-23)
Primary citation	Vanhooke, J.L.,Benning, M.M.,Bauer, C.B.,Pike, J.W.,DeLuca, H.F. Molecular Structure of the Rat Vitamin D Receptor Ligand Binding Domain Complexed with 2-Carbon-Substituted Vitamin D(3) Hormone Analogues and a LXXLL-Containing Coactivator Peptide Biochemistry, 43:4101-4110, 2004 Cited by PubMed: 15065852 DOI: 10.1021/bi036056y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation