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1RF2

Cholera Toxin B-Pentamer Complexed With Bivalent Nitrophenol-Galactoside Ligand BV4

Summary for 1RF2
Entry DOI10.2210/pdb1rf2/pdb
Related1RCV 1RD9 1RDP
Descriptorcholera toxin B protein (CTB), 1,3-BIS-([3-[3-[3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYLAMINO-3,4-DIOXO-CYCLOBUTENYL]-AMINO-PROPOXY-ETHOXY-ETHOXY]-PROPYL-]AMINO-CARBONYLOXY)-2-AMINO-PROPANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
Functional Keywordsbivalent, cholera, toxin, pentamer, complex
Biological sourceVibrio cholerae
Cellular locationSecreted: P01556
Total number of polymer chains5
Total formula weight67363.17
Authors
Pickens, J.C.,Mitchell, D.D.,Liu, J.,Tan, X.,Zhang, Z.,Verlinde, C.L.,Hol, W.G.,Fan, E. (deposition date: 2003-11-07, release date: 2004-10-26, Last modification date: 2023-08-23)
Primary citationPickens, J.C.,Mitchell, D.D.,Liu, J.,Tan, X.,Zhang, Z.,Verlinde, C.L.,Hol, W.G.,Fan, E.
Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer.
Chem.Biol., 11:1205-1215, 2004
Cited by
PubMed: 15380181
DOI: 10.1016/j.chembiol.2004.06.008
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.35 Å)
Structure validation

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