1RDH

CRYSTALLOGRAPHIC ANALYSES OF AN ACTIVE HIV-1 RIBONUCLEASE H DOMAIN SHOW STRUCTURAL FEATURES THAT DISTINGUISH IT FROM THE INACTIVE FORM

1RDH の概要

• エントリーDOI: 10.2210/pdb1rdh/pdb
• 分子名称: HIV-1 REVERSE TRANSCRIPTASE (RIBONUCLEASE H DOMAIN) (1 entity in total)
• 機能のキーワード: hydrolase(endoribonuclease)
• 由来する生物種: Human immunodeficiency virus 1
• 細胞内の位置: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03366
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32392.73

構造登録者

Finzel, B.C.,Chattopadhyay, D.,Einspahr, H.M. (登録日: 1993-03-05, 公開日: 1994-05-31, 最終更新日: 2024-02-14)

• 主引用文献: Chattopadhyay, D.,Finzel, B.C.,Munson, S.H.,Evans, D.B.,Sharma, S.K.,Strakalaitus, N.A.,Brunner, D.P.,Eckenrode, F.M.,Dauter, Z.,Betzel, C.,Einspahr, H.M.; Crystallographic analyses of an active HIV-1 ribonuclease H domain show structural features that distinguish it from the inactive form.; Acta Crystallogr.,Sect.D, 49:423-427, 1993; PubMed: 15299518; DOI: 10.1107/S0907444993002409

実験手法

X-RAY DIFFRACTION (2.8 Å)