1RDH
CRYSTALLOGRAPHIC ANALYSES OF AN ACTIVE HIV-1 RIBONUCLEASE H DOMAIN SHOW STRUCTURAL FEATURES THAT DISTINGUISH IT FROM THE INACTIVE FORM
Summary for 1RDH
Entry DOI | 10.2210/pdb1rdh/pdb |
Descriptor | HIV-1 REVERSE TRANSCRIPTASE (RIBONUCLEASE H DOMAIN) (1 entity in total) |
Functional Keywords | hydrolase(endoribonuclease) |
Biological source | Human immunodeficiency virus 1 |
Cellular location | Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03366 |
Total number of polymer chains | 2 |
Total formula weight | 32392.73 |
Authors | Finzel, B.C.,Chattopadhyay, D.,Einspahr, H.M. (deposition date: 1993-03-05, release date: 1994-05-31, Last modification date: 2024-02-14) |
Primary citation | Chattopadhyay, D.,Finzel, B.C.,Munson, S.H.,Evans, D.B.,Sharma, S.K.,Strakalaitus, N.A.,Brunner, D.P.,Eckenrode, F.M.,Dauter, Z.,Betzel, C.,Einspahr, H.M. Crystallographic analyses of an active HIV-1 ribonuclease H domain show structural features that distinguish it from the inactive form. Acta Crystallogr.,Sect.D, 49:423-427, 1993 Cited by PubMed: 15299518DOI: 10.1107/S0907444993002409 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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